A 77-Year-Old Man with a Prolonged Activated Partial Thromboplastin Time

A 77-year-old man with a prolonged activated partial thromboplastin time.

A 77-year-old man was admitted to another hospital because of increasing dyspnea and edema of the lower limbs. The patient reported a loss of appetite and a flu-like illness 4 weeks previously. He was on various medications for heart failure, including metoprolol, ramipril, spironolactone, torasemide, metformin, and digoxin. For chronic atrial fibrillation, the patient had received dabigatran (...

Laboratory Methodologic Approach in Prolonged Activated Partial Thromboplastin Time Test

The pathological activated partial thromboplastin time test is a data that we can find in all clinical laboratories routinely. The hemato-coagulative clinical case here reported aims to point out how the laboratory can provide a correct diagnosis by methodological rational setting and, consequently, carry out an appropriate therapy, or reassure the patient that the pathological data will not ca...

A Patient with a Prolonged Activated Partial Thromboplastin Time and a Deep Intracerebral Haemorrhage

We report on a 57-year-old woman with a pontine haemorrhage and an extremely prolonged activated partial thromboplastin time (aPTT) of more than 240 s, suggestive of a coagulation disorder. Given the location of the haemorrhage, which is associated with a high mortality rate, recombinant factor VIIa was administered, although not all necessary laboratory analyses could be performed at that time...

Sequential thrombosis and bleeding in a woman with a prolonged activated partial thromboplastin time

Simultaneous or sequential haemorrhage and thrombosis in the presence of a prolonged activated partial thromboplastin time (aPTT) is a rare occurrence: we describe the case a 37 year old lady who developed post-delivery deep vein thrombosis treated with low molecular heparin and warfarin followed a week later by extensive bruising over legs and forearms, a significant drop in haemoglobin and a ...

A 77-year-old man with nonvariceal upper gastrointestinal bleeding.